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96-channel automated liquid handler
µL Magic 96
Miniaturize assays without touch-off.
A high-throughput Differential Pipetting™ platform built to aspirate small volumes accurately and dispense them cleanly, contact-free—combining fine resolution and high flow in the same 96-channel head.

Built for practical automation
Nanoliter-scale control with the delivery force labs need.
Conventional low-volume systems often trade aspiration resolution for dispensing force. µL Magic 96 uses DRD’s dual-piston Differential Displacement™ architecture to address both requirements inside one compact liquid-handling core.
The result is a platform designed for miniaturized assays, dense plates, expensive reagents, and workflows where hanging drops or touch-off variability are unacceptable.
Demonstrated performance
From 96 aspirations to a complete 384-well plate.
An intuitive up/down sequence divides delivery into four plate quadrants while preserving the same low-volume aspiration and contact-free release principle.

Accurate small-volume aspiration
Differential motion creates fine net displacement while maintaining useful mechanical travel.
Contact-free delivery
High-flow operation blows the sample cleanly into the destination without touch-off.
Dense-plate throughput
Ninety-six channels serve four quadrants of a 384-well plate in a repeatable sequence.
Consistent placement
Demonstrations show microliter samples positioned at the bottom of each well after dispensing from above.
Performance statements summarize DRD demonstrations and supplied product materials. Application-specific validation is recommended.
Clean two-step workflow
Aspirate with precision. Dispense with power.
The system changes piston behavior—not the basic logic of liquid transfer—making the workflow familiar to operators and automation teams.

Aspirate accurately
Two pistons move together. The difference in their effective areas produces a much smaller net liquid displacement.
Release completely
A piston operates independently to create the flow needed to clear the tip without touching the destination.


Differential Displacement™ inside
Two pistons can move together—or independently.
The paired pistons deliver differential resolution when they move together. Independent motion unlocks higher flow for contact-free dispensing and vigorous liquid movement.
- Fine low-volume controlSmall effective displacement from the difference between piston diameters.
- No hanging-drop dependencyClean delivery is designed to avoid touch-off-and-drag workarounds.
- OEM-ready architectureThe liquid-handling core can support instrument and integrated-module pathways.
Where µL Magic 96 fits
High-density workflows with less reagent and less complexity.
Designed for teams moving toward smaller assay volumes without adding fragile touch-off choreography.
High-throughput screening
384- / 1536-well assays
Cell-based assays
NGS & genomics
Diagnostics sample preparation
Reagent-sparing miniaturization
Evaluate µL Magic 96